產(chǎn)品編號 | bs-19733R-BF488 |
英文名稱1 | Rabbit Anti-RASEF/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的ras基因相關(guān)蛋白Rab45抗體 |
別 名 | FLJ31614; RAB45; RAB45 member RAS oncogene family; RASEF_HUMAN; RAS and EF hand domain containing; RAS and EF hand domain containing protein; Ras related protein Rab 45. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 83kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RASEF |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012] Function: Binds predominantly GDP, and also GTP. Subcellular Location: Cytoplasm, perinuclear region. Tissue Specificity: Down-regulated in cutaneous melanoma cells but not in breast cancer cells. Similarity: Belongs to the small GTPase superfamily. Rab family. Database links: Entrez Gene: 158158 Human Entrez Gene: 242505 Mouse Omim: 611344 Human SwissProt: Q8IZ41 Human SwissProt: Q5RI75 Mouse Unigene: 657750 Human Unigene: 487185 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |