產(chǎn)品編號(hào) | bs-19970R-Gold |
英文名稱1 | Rabbit Anti-PPP2R5A/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的蛋白磷酸酶2調(diào)節(jié)亞基5A抗體 |
別 名 | 2A5A_HUMAN; B56A; MGC131915; PP2A B subunit B' alpha isoform; PP2A B subunit B56 alpha isoform; PP2A B subunit isoform B''-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A B subunit PR61 alpha isoform; PP2A B subunit R5 alpha isoform; PPP2R5A; PR61A; PR61alpha; Protein phosphatase 2 regulatory subunit B (B56) alpha isoform; Protein phosphatase 2 regulatory subunit B alpha isoform; Protein phosphatase 2 regulatory subunit B' alpha; Serine/threonine protein phosphatase 2A 56kDa regulatory subunit alpha isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 56kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PPP2R5A |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Subcellular Location: Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase. Tissue Specificity: Widely expressed with the highest expression in heart and skeletal muscle. Post-translational modifications: Phosphorylated on serine residues. Similarity: Belongs to the phosphatase 2A regulatory subunit B56 family. Database links: Entrez Gene: 5525 Human Entrez Gene: 226849 Mouse Omim: 601643 Human SwissProt: Q15172 Human SwissProt: Q6PD03 Mouse Unigene: 497684 Human Unigene: 205569 Mouse Unigene: 104461 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |