| 產(chǎn)品編號(hào) | bs-19958R-Gold |
| 英文名稱(chēng)1 | Rabbit Anti-PREB/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的催乳素調(diào)節(jié)元件結(jié)合蛋白PREB抗體 |
| 別 名 | Mammalian guanine nucleotide exchange factor mSec12; Preb; PREB_HUMAN; Prolactin regulatory binding element protein; Prolactin regulatory element binding; Prolactin regulatory element binding protein; Prolactin regulatory element-binding protein; SEC12. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 生長(zhǎng)因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PREB |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008] Function: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER. Subcellular Location: Nucleus. Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitous. Similarity: Contains 3 WD repeats. Database links: Entrez Gene: 10113 Human Entrez Gene: 50907 Mouse Omim: 606395 Human SwissProt: Q9HCU5 Human SwissProt: Q9WUQ2 Mouse Unigene: 279784 Human Unigene: 272414 Mouse Unigene: 41899 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
