產(chǎn)品編號 | bs-19878R-Gold |
英文名稱1 | Rabbit Anti-Rhophilin 2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的Rho結(jié)合蛋白2抗體 |
別 名 | 76 kDa RhoB effector protein; D7Ertd784e; GTP Rho binding protein 2; GTP-Rho-binding protein 2; p76RBE; Rho GTPase binding protein 2; RhoB effector; RhoBP; Rhophilin 2; Rhophilin; Rhophilin like protein; Rhophilin like Rho GTPase binding protein; Rhophilin Rho GTPase binding protein 2; Rhophilin-2; Rhophilin2; RHPN 2; RHPN2; RHPN2_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 77kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Rhophilin 2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009] Function: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Subunit: Interacts with GTP-bound RhoA and RhoB. Subcellular Location: Cytoplasm > perinuclear region. Tissue Specificity: Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver. Similarity: Belongs to the RHPN family. Contains 1 BRO1 domain. Contains 1 PDZ (DHR) domain. Contains 1 REM (Hr1) repeat. Database links: Entrez Gene: 85415 Human Entrez Gene: 52428 Mouse SwissProt: Q8IUC4 Human SwissProt: Q8BWR8 Mouse Unigene: 466435 Human Unigene: 286600 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |