產(chǎn)品編號 | bs-19560R-Cy5 |
英文名稱1 | Rabbit Anti-OBFC1/Cy5 Conjugated antibody |
中文名稱 | Cy5標記的α輔助因子44抗體 |
別 名 | AAF 44; AAF44; Alpha accessory factor 44; bA541N10.2; CST complex subunit STN1; FLJ22559; Obfc1; Oligonucleotide/oligosaccharide binding fold containing 1; Oligonucleotide/oligosaccharide-binding fold-containing protein 1; OTTHUMP00000020417; OTTHUMP00000020418; Replication protein A 32 kDa subunit; RP11-541N10.2; RPA 32; STN1; STN1_HUMAN; Suppressor of cdc thirteen; Suppressor of cdc thirteen homolog. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 結(jié)合蛋白 表觀遺傳學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human, Mouse, Rat, Horse, ) |
產(chǎn)品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OBFC1/AAF44 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009] Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Subcellular Location: Nucleus. Chromosome > telomere. Similarity: Belongs to the STN1 family. Contains 1 OB DNA-binding domain. Database links: Entrez Gene: 79991 Human Entrez Gene: 108689 Mouse Omim: 613128 Human SwissProt: Q9H668 Human SwissProt: Q8K2X3 Mouse Unigene: 62314 Human Unigene: 218048 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |