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Rabbit Anti-NUP155/PE-Cy3 Conjugated antibody (bs-19543R-PE-Cy3)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19543R-PE-Cy3
英文名稱1 Rabbit Anti-NUP155/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的核孔復合蛋白Nup155抗體
別    名 155 kDa nucleoporin; D930027M19Rik; KIAA0791; mKIAA0791; N155; NU155_HUMAN; Nuclear pore complex protein Nup155; nucleoporin 155kD; Nucleoporin Nup155; Nup155.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Zebrafish, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 155kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUP155
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]

Function:
Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.

Subcellular Location:
Nucleus > nuclear pore complex. Nucleus membrane. Nucleus membrane. In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis.

Tissue Specificity:
Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Post-translational modifications:
Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a role in the reversible disassembly of the nuclear pore complex during mitosis.

Similarity:
Belongs to the non-repetitive/WGA-negative nucleoporin family.

Database links:

Entrez Gene: 9631 Human

Entrez Gene: 427443 Chicken

Entrez Gene: 461913 Chimpanzee

Entrez Gene: 506738 Cow

Entrez Gene: 479360 Dog

Entrez Gene: 101133763 Gorilla

Entrez Gene: 100053405 Horse

Entrez Gene: 170762 Mouse

Entrez Gene: 100437988 Orangutan

Entrez Gene: 100517061 Pig

Entrez Gene: 100347238 Rabbit

Entrez Gene: 117021 Rat

Entrez Gene: 706019 Rhesus monkey

Entrez Gene: 380494 Xenopus laevis

Entrez Gene: 100379911 Xenopus tropicalis

Omim: 606694 Human

SwissProt: O75694 Human

SwissProt: Q99P88 Mouse

SwissProt: P37199 Rat

Unigene: 547696 Human

Unigene: 295168 Mouse

Unigene: 11328 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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