| 產(chǎn)品編號 | bs-19541R-BF350 |
| 英文名稱1 | Rabbit Anti-NUFIP1/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的NUFIP1蛋白抗體 |
| 別 名 | bA540M5.1; Nuclear FMRP interacting protein 1; Nuclear fragile X mental retardation interacting protein 1; nuclear fragile X mental retardation protein interacting protein 1; NUFIP. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chimpanzee, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 70kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUDT9 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012] Function: NUFIP1 contains 1 C2H2- type zinc finger and binds RNA. It interacts with FMR1. NUFIP1 may be associated with preinitiation complexes, open transcription complexes, and elongation complexes. It may facilitate ATP-dependent dissociation of hyperphosphorylated pol II from open transcription complexes. Subcellular Location: Nuclear Database links: Entrez Gene: 26747 Human Omim: 604354 Human SwissProt: Q9UHK0 Human Unigene: 525006 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
