產(chǎn)品編號(hào) | bs-19605R-APC |
英文名稱1 | Rabbit Anti-SDPR/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的磷脂酰絲氨酸結(jié)合蛋白SDPR抗體 |
別 名 | Cavin 2; Cavin-2; Phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS p68; PS-p68; Sdpr; SDPR_HUMAN; SDR; Serum deprivation response; Serum deprivation response protein; Serum deprivation-response protein. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 結(jié)合蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Cow, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 47kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SDPR |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009] Function: May play a role in targeting PRKCA to caveolae. Subcellular Location: Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae. Tissue Specificity: Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. Post-translational modifications: Phosphorylated on Ser residues. Similarity: Belongs to the PTRF/SDPR family. Database links: Entrez Gene: 8436 Human Entrez Gene: 20324 Mouse Omim: 606728 Human SwissProt: O95810 Human SwissProt: Q63918 Mouse Unigene: 26530 Human Unigene: 480575 Mouse Unigene: 203035 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |