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Rabbit Anti-phospho-FOXO6 (Ser184)/BF647 Conjugated antibody (bs-20061R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-20061R-BF647
英文名稱1 Rabbit Anti-phospho-FOXO6 (Ser184)/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的磷酸化叉頭蛋白O6抗體
別    名 Foxo6 (phospho Ser184); Foxo6 (phospho S184); Forkhead box protein O6; FOXO6_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human FOXO6 around the phosphorylation site of Ser184
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons.

Function:
Transcriptional activator.

Subcellular Location:
Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.

Post-translational modifications:
Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 100132074 Human

Entrez Gene: 329934 Mouse

Entrez Gene: 313558 Rat

Omim: 611457 Human

SwissProt: A8MYZ6 Human

SwissProt: Q70KY4 Mouse

Unigene: 277090 Mouse

Unigene: 190858 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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