| 產(chǎn)品編號(hào) | bs-18935R-PE |
| 英文名稱(chēng)1 | Rabbit Anti-MICALL1/MIRab13/PE Conjugated antibody |
| 中文名稱(chēng) | PE標(biāo)記的MICAL樣蛋白1抗體 |
| 別 名 | DKFZp686M2226; FLJ45921; KIAA1668; MICAL-L1; MICAL-like 1; MICAL-like protein 1; Micall1; MILK1_HUMAN; MIRab13; Molecule interacting with Rab13. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 93kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MICALL1/MIRab13 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Function: May be a cytoskeletal regulator. Subcellular Location: Cytoplasm > cytoskeleton. Similarity: Contains 1 CH (calponin-homology) domain. Contains 1 LIM zinc-binding domain. Database links: Entrez Gene: 85377 Human SwissProt: Q8N3F8 Human Unigene: 517610 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
