| 產(chǎn)品編號(hào) | bs-18889R-Cy7 |
| 英文名稱1 | Rabbit Anti-NgR2/RTN4RL2/Cy7 Conjugated antibody |
| 中文名稱 | Cy7標(biāo)記的NOGO66受體相關(guān)蛋白2抗體 |
| 別 名 | NgR2; NGRH1; NGRL3; Nogo 66 receptor related protein 2; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; R4RL2_HUMAN; Reticulon-4 receptor-like 2; RTN4RL2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NgR2/RTN4RL2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: NgR2 belongs to the Nogo receptor family and contains eight LRR (leucine-rich) repeats, one LRRNT domain and a single LRRCT domain. The gene encoding NgR2 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Subcellular Location: Cell membrane Tissue Specificity: Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid. Post-translational modifications: Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein. Similarity: Belongs to the Nogo receptor family. Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 349667 Human Entrez Gene: 269295 Mouse Omim: 610462 Human SwissProt: Q86UN3 Human SwissProt: Q7M6Z0 Mouse Unigene: 502618 Human Unigene: 389289 Mouse Unigene: 86447 Mouse Unigene: 162683 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
