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Rabbit Anti-PDE10A/Gold Conjugated antibody (bs-18883R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-18883R-Gold
英文名稱1 Rabbit Anti-PDE10A/Gold Conjugated antibody
中文名稱 膠體金標記的磷酸二酯酶10A抗體
別    名 5''-cyclic phosphodiesterase 10A; cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3''; cAMP and cAMP-inhibited cGMP 3'5'-cyclic phosphodiesterase 10A; FLJ11894; HSPDE 10A; HSPDE10A; PDE 10A; PDE10_HUMAN; Pde10a; Phosphodiesterase 10A; Phosphodiesterase 10A1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE10A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]

Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.

Subcellular Location:
Cytoplasm. Located mostly to soluble cellular fractions.

Tissue Specificity:
Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. Contains 2 GAF domains.

Database links:

Entrez Gene: 10846 Human

Entrez Gene: 23984 Mouse

Entrez Gene: 63885 Rat

Omim: 610652 Human

SwissProt: Q9Y233 Human

SwissProt: Q8CA95 Mouse

SwissProt: Q9QYJ6 Rat

Unigene: 348762 Human

Unigene: 87161 Mouse

Unigene: 44869 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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