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Rabbit Anti-RT33/MRPS33/Biotin Conjugated antibody (bs-18882R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-18882R-Bio
英文名稱1 Rabbit Anti-RT33/MRPS33/Biotin Conjugated antibody
中文名稱 生物素標記的28S核糖體蛋白S33抗體
別    名 28S ribosomal protein S33; 28S ribosomal protein S33, mitochondrial; AI841153; CGI 139; FLJ21123; Ganglioside induced differentiation associated protein 3; Gdap3; MGC106490; mitochondrial; MRP S33; MRP-S33; MRPS33; OTTHUMP00000212181; OTTMUSP00000028636; OTTMUSP00000028637; PTD003; RT33_HUMAN; S33mt.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RT33/MRPS33
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008]

Function:
Displays low GTPase activity and exist predominantly in the GTP-bound form.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Highly expressed in heart and brain.

Similarity:
Belongs to the small GTPase superfamily. Di-Ras family.

Database links:

Entrez Gene: 51650 Human

Entrez Gene: 14548 Mouse

Omim: 611993 Human

SwissProt: Q9Y291 Human

SwissProt: Q9D2R8 Mouse

Unigene: 416207 Human

Unigene: 377071 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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