| 產(chǎn)品編號(hào) | bs-19050R-Gold |
| 英文名稱1 | Rabbit Anti-NCKX2/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的視網(wǎng)膜鈉/鉀/鈣交換體2抗體 |
| 別 名 | Na(+)/K(+)/Ca(2+) exchange protein 2; Na(+)/K(+)/Ca(2+)-exchange protein 2; NCKX 2; NCKX2_HUMAN; OTTHUMP00000045115; Retinal cone Na Ca+K exchanger; Retinal cone Na-Ca+K exchanger; SLC24A2; Sodium/potassium/calcium exchanger 2; solute carrier family 24 (sodium/potassium/calcium exchanger) member 2; Solute carrier family 24 member 2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 74kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NCKX2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Function: Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Subcellular Location: Membrane. Similarity: Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily. Database links: Entrez Gene: 25769 Human Entrez Gene: 76376 Mouse Omim: 609838 Human SwissProt: Q9UI40 Human Unigene: 283014 Human Unigene: 208755 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
