| 產(chǎn)品編號(hào) | bs-18723R-BF647 |
| 英文名稱1 | Rabbit Anti-MCF2L2/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的MCF2變換序列樣蛋白2抗體 |
| 別 名 | ARHGEF22; Dbs related Rho family guanine nucleotide exchange factor; Dbs-related Rho family guanine nucleotide exchange factor; DKFZp686K0690; DRG; FLJ42509; KIAA0861; MCF.2 cell line derived transforming sequence like 2; MCF2 transforming sequence like protein 2; MCF2-transforming sequence-like protein 2; MCF2L2; MF2L2_HUMAN; Probable guanine nucleotide exchange factor MCF2L2; Rho family guanine nucleotide exchange factor. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 127kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MCF2L2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: MCF2L2 is a 1,114 amino acid protein that contains one spectrin repeat, one PH domain, one DH domain and one CRAL-TRIO domain. Expressed at high levels in brain and also present in testis and pancreas, MCF2L2 is thought to function as a GEF, catalyzing the activation of target GTPases. Variations in the gene encoding MCF2L2 may be associated with an increased susceptibility to type 2 diabetes. Multiple isoforms of MCF2L2 exist due to alternative splicing events. Function: Probably functions as a guanine nucleotide exchange factor. Tissue Specificity: Significantly expressed in brain and modestly in pancreas, brain and testis. DISEASE: Genetic variation in MCF2L2 may be associated with susceptibility to noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type 2. Similarity: Belongs to the MCF2 family. Contains 1 CRAL-TRIO domain. Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. Contains 1 spectrin repeat. Database links: Entrez Gene: 23101 Human SwissProt: Q86YR7 Human Unigene: 208267 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
