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Rabbit Anti-MAMSTR/BF594 Conjugated antibody (bs-18642R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18642R-BF594
英文名稱1 Rabbit Anti-MAMSTR/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的MAMSTR蛋白抗體
別    名 2810022D01Rik; 5430432N15Rik; AW743872; FLJ36070; Likely ortholog of MEF2 activating SAP transcriptional regulator; MAMSTR; MASTR; MASTR_HUMAN; MEF2 activating SAP transcriptional regulator; MEF2-activating motif and SAP domain-containing transcriptional regulator; MEF2-activating SAP transcriptional regulatory protein; MGC117259.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAMSTR
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
MAMSTR is a 415 amino acid nuclear protein that functions as a transcriptional coactivator by stimulating MEF-2. Containing one SAP domain, MAMSTR is expressed in spleen, placenta, skeletal muscle and brain, and exists as three alternatively spliced isoforms. The gene encoding MAMSTR maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Function:
Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in skeletal muscle, brain, placenta and spleen.

Similarity:
Contains 1 SAP domain.

Database links:

Entrez Gene: 284358 Human

Omim: 610349 Human

SwissProt: Q6ZN01 Human

Unigene: 191815 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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