產(chǎn)品編號(hào) | bs-18642R-BF350 |
英文名稱(chēng)1 | Rabbit Anti-MAMSTR/BF350 Conjugated antibody |
中文名稱(chēng) | BF350標(biāo)記的MAMSTR蛋白抗體 |
別 名 | 2810022D01Rik; 5430432N15Rik; AW743872; FLJ36070; Likely ortholog of MEF2 activating SAP transcriptional regulator; MAMSTR; MASTR; MASTR_HUMAN; MEF2 activating SAP transcriptional regulator; MEF2-activating motif and SAP domain-containing transcriptional regulator; MEF2-activating SAP transcriptional regulatory protein; MGC117259. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MAMSTR |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: MAMSTR is a 415 amino acid nuclear protein that functions as a transcriptional coactivator by stimulating MEF-2. Containing one SAP domain, MAMSTR is expressed in spleen, placenta, skeletal muscle and brain, and exists as three alternatively spliced isoforms. The gene encoding MAMSTR maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Function: Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation. Subcellular Location: Nucleus. Tissue Specificity: Expressed in skeletal muscle, brain, placenta and spleen. Similarity: Contains 1 SAP domain. Database links: Entrez Gene: 284358 Human Omim: 610349 Human SwissProt: Q6ZN01 Human Unigene: 191815 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |