| 產(chǎn)品編號 | bs-17625R-Gold |
| 英文名稱1 | Rabbit Anti-SPATA20/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的精子發(fā)生相關(guān)蛋白20抗體 |
| 別 名 | SPATA20; Sperm protein SSP411; Sperm-specific protein 411; Spermatogenesis associated 20; Spermatogenesis-associated protein 20; SPT20_HUMAN; Ssp411; Tisp78; Transcript increased in spermiogenesis 78. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 干細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPATA20 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: SPATA20 is a 786 amino acid protein that may be involved in fertility regulation. SPATA20 is expressed in testis in an age dependent manner and localizes to round and elongated spermatids. SPATA20 contains a conserved thioredoxin-like domain near the N-terminus region and exists as four isoforms produced by alternative splicing events. SPATA20 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function: May play a role in fertility regulation. Subcellular Location: Secreted. Database links: Entrez Gene: 100714104 Guinea pig Entrez Gene: 100069987 Horse Entrez Gene: 64847 Human Entrez Gene: 217116 Mouse Omim: 613939 Human SwissProt: Q8TB22 Human SwissProt: Q80YT5 Mouse Unigene: 103147 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
