| 產(chǎn)品編號(hào) | bs-18063R-APC |
| 英文名稱1 | Rabbit Anti-HNMT/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的組織胺N-甲基轉(zhuǎn)移酶抗體 |
| 別 名 | EC 2.1.1.8; Histamine N methyltransferase; Histamine N-methyltransferase; HMT; Hnmt; HNMT S1; HNMT S2; HNMT_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HNMT |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008] Function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. Subcellular Location: Cytoplasm. Similarity: Belongs to the methyltransferase superfamily. HNMT family. Database links: Entrez Gene: 3176 Human Omim: 605238 Human SwissProt: P50135 Human Unigene: 42151 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
