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Rabbit Anti-MTMR12/BF350 Conjugated antibody (bs-17884R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17884R-BF350
英文名稱1 Rabbit Anti-MTMR12/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的肌微管素相關(guān)蛋白12抗體
別    名 3 PAP; 3 phosphatase adapter protein; 3 phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter protein; 3PAP; KIAA1682; Mtmr12; MTMRC_HUMAN; Myotubularin related protein 12; Myotubularin-related protein 12; Phosphatidylinositol 3 phosphate 3 phosphatase adapter subunit; Phosphatidylinositol 3 phosphate associated protein; Phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit; PIP3AP.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Horse, Rabbit, Sheep, Cat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTMR12
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Function:
Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.

Subcellular Location:
Cytoplasm. Localizes to punctate vesicles when associated with MTM1.

Tissue Specificity:
Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung.

Similarity:
Belongs to the protein-tyrosine phosphatase family.
Non-receptor class myotubularin subfamily. Contains 1 myotubularin
phosphatase domain.

Database links:

Entrez Gene: 54545 Human

Entrez Gene: 268783 Mouse

Entrez Gene: 310155 Rat

Entrez Gene: 569130 Zebrafish

Omim: 606501 Human

SwissProt: Q9C0I1 Human

SwissProt: Q80TA6 Mouse

SwissProt: Q5FVM6 Rat

SwissProt: A2BGG1 Zebrafish

Unigene: 481836 Human

Unigene: 54460 Mouse

Unigene: 214625 Rat

Unigene: 87790 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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