產(chǎn)品編號 | bs-10738R-Gold |
英文名稱1 | Rabbit Anti-SLC19A2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的SLC19A2抗體 |
別 名 | Thiamine transporter 1; S19A2_HUMAN; SLC19A2; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; THT1; ThTr 1; ThTr-1; ThTr1; TRMA. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 55kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC19A2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. [provided by RefSeq, Jul 2008] Function: High-affinity transporter for the intake of thiamine. Subcellular Location: Membrane. Tissue Specificity: Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung. DISEASE: Defects in SLC19A2 are the cause of thiamine-responsive megaloblastic anemia syndrome (TRMA) [MIM:249270]; also known as Rogers syndrome. TRMA is an autosomal recessive disease with features that include megaloblastic anemia, mild thrombocytopenia and leucopenia, sensorineural deafness and diabetes mellitus. Similarity: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. Database links: Entrez Gene: 10560 Human Entrez Gene: 116914 Mouse Omim: 603941 Human SwissProt: O60779 Human SwissProt: Q9EQN9 Mouse Unigene: 30246 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |