產(chǎn)品編號(hào) | bs-17352R-Gold |
英文名稱1 | Rabbit Anti-Homer (1b+1c)/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的神經(jīng)細(xì)胞早期基因抗體 |
別 名 | Homer 1; HOMER; Homer homolog 1; Homer protein homolog 1; Homer1; HOMER1B; HOMER1C; Neuronal immediate early gene; SYN47; Ves 1. HOME1_HUMAN |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞類型標(biāo)志物 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Rat, (predicted: Mouse, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Homer (1b+1c) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008] Function: Homer is a neuronal immediate early gene that is enriched at excitatory synapses and selectively binds metabotropic glutamate receptors. Subunit: Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2,SHANK1 and SHANK3. Interacts with IFT57 and OPHN1. Isoform 1 encodes a coiled-coil structure that mediates homo- and heteromultimerization. Subcellular Location: Cytoplasmic; Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Postsynaptic density of neuronal cells. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the endoplasmic reticulum. Similarity: Belongs to the Homer family. Contains 1 WH1 domain. Database links: Entrez Gene: 9456 Human Entrez Gene: 26556 Mouse Omim: 604798 Human SwissProt: Q86YM7 Human SwissProt: Q9Z2Y3 Mouse Unigene: 591761 Human Unigene: 37500 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |