| 產(chǎn)品編號(hào) | bs-17175R-PE-Cy5 |
| 英文名稱1 | Rabbit Anti-TPRKB/PE-Cy5 Conjugated antibody |
| 中文名稱 | PE-Cy5標(biāo)記的p53相關(guān)蛋白激酶結(jié)合蛋白抗體 |
| 別 名 | CGI 121; My019; PRPK (p53 related protein kinase) binding protein; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TPRKB |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity). Subunit: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes. Interacts with TP53RK/PRPK. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed. Similarity: Belongs to the CGI121/TPRKB family. Database links: Entrez Gene: 425906 Chicken Entrez Gene: 51002 Human Entrez Gene: 69786 Mouse Omim: 608680 Human SwissProt: Q9Y3C4 Human SwissProt: Q8QZZ7 Mouse Unigene: 157401 Human Unigene: 218434 Mouse Unigene: 203015 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
