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Rabbit Anti-GSTM5/Gold Conjugated antibody (bs-16343R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16343R-Gold
英文名稱1 Rabbit Anti-GSTM5/Gold Conjugated antibody
中文名稱 膠體金標記的谷胱甘肽S轉(zhuǎn)移酶M5抗體
別    名 Glutathione S alkyltransferase M5; Glutathione S aralkyltransferase M5; Glutathione S aryltransferase M5; Glutathione S transferase M5; Glutathione S transferase Mu 5; Glutathione S-transferase Mu 5; GST class mu 5; GST class-mu 5; GSTM 5; GSTM5 5; Gstm5; GSTM5-5; GSTM5_HUMAN; GTM 5; GTM5; OTTHUMP00000013359; OTTHUMP00000013361; S (hydroxyalkyl)glutathione lyase M5.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GSTM5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]

Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the GST superfamily. Mu family.
Contains 1 GST C-terminal domain.
Contains 1 GST N-terminal domain.

Database links:

Entrez Gene: 2949 Human

Entrez Gene: 14866 Mouse

Entrez Gene: 64352 Rat

Omim: 138385 Human

SwissProt: P46439 Human

SwissProt: P48774 Mouse

SwissProt: Q9Z1B2 Rat

Unigene: 75652 Human

Unigene: 282351 Mouse

Unigene: 9158 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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