產(chǎn)品編號(hào) | bs-16329R-Gold |
英文名稱(chēng)1 | Rabbit Anti-GRXCR1/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的GRXCR1蛋白抗體 |
別 名 | DFNB25; Glutaredoxin domain-containing cysteine-rich protein 1; Glutaredoxin, cysteine rich 1; GRCR1_HUMAN; Grxcr1. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 32kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GRXCR1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010] Function: Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea. Subcellular Location: Cell projection; stereocilium. Cell projection > microvillus. Cell projection; kinocilium. In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. DISEASE: Defects in GRXCR1 are the cause of deafness autosomal recessive type 25 (DFNB25) [MIM:613285]. DFNB25 is characterized by moderate to severe or profound hearing loss which is progressive in some individuals but not in others. Speech development is impaired in some but not all affected individuals and vestibular dysfunction is observed in some affected individuals. Similarity: Belongs to the GRXCR1 family. Contains 1 glutaredoxin domain. Database links: Entrez Gene: 389207 Human Omim: 613283 Human SwissProt: A8MXD5 Human Unigene: 162559 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |