產(chǎn)品編號(hào) | bs-16781R-Gold |
英文名稱1 | Rabbit Anti-KLRC3/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的殺傷細(xì)胞凝集素樣受體C亞家族成員3抗體 |
別 名 | Killer cell lectin like receptor subfamily C member 3; KLRC 3; KLRC3; NK cell receptor E; NKG2 E activating NK receptor; NKG2 E; NKG2 E type II integral membrane protein; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NKG2E activating NK receptor; NKG2E; NKG2E type II integral membrane protein; NKG2E_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 淋巴細(xì)胞 t-淋巴細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 27kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KLRC3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subcellular Location: Membrane. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 3823 Human Entrez Gene: 58179 Mouse Omim: 602892 Human SwissProt: Q07444 Human Unigene: 654362 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |