產(chǎn)品編號(hào) | bs-16528R-Gold |
英文名稱1 | Rabbit Anti-HSD17B7/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的17β羥類固醇脫氫酶7抗體 |
別 名 | 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; 3-keto-steroid reductase; DHB7_HUMAN; Estradiol 17 beta dehydrogenase 7; Estradiol 17-beta-dehydrogenase 7; Hsd17b7; hydroxysteroid (17 beta) dehydrogenase 7; MGC12523; MGC75018; PRAP; SDR37C1; Short chain dehydrogenase/reductase family 37C member 1. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 細(xì)胞膜蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 33kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HSD17B7 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010] Function: Responsible for the reduction of the keto group on the C-3 of sterols. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells. Post-translational modifications: Phosphorylated. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily. Database links: Entrez Gene: 51478 Human Entrez Gene: 15490 Mouse Omim: 606756 Human SwissProt: P56937 Human SwissProt: O88736 Mouse Unigene: 492925 Human Unigene: 12882 Mouse Unigene: 7040 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |