| 產(chǎn)品編號(hào) | bs-16099R-BF488 |
| 英文名稱1 | Rabbit Anti-FMO4/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的肝黃素單加氧酶4抗體 |
| 別 名 | Flavin containing monooxygenase 4; Dimethylaniline monooxygenase [N oxide forming] 4; Dimethylaniline monooxygenase [N-oxide-forming] 4; Dimethylaniline monooxygenase 4; Dimethylaniline oxidase 4; FMO 2; FMO 4; FMO2; Fmo4; FMO4_HUMAN; Hepatic flavin containing monooxygenase 4; Hepatic flavin-containing monooxygenase 4; OTTHUMP00000060454. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 63kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FMO4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Sep 2013] Function: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Liver. Similarity: Belongs to the FMO family. Database links: Entrez Gene: 2329 Human Omim: 136131 Human SwissProt: P31512 Human Unigene: 386502 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
