產(chǎn)品編號(hào) | bs-14417R-Gold |
英文名稱(chēng)1 | Rabbit Anti-DPH4/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的DPH4蛋白抗體 |
別 名 | 1700030A21Rik; 2610027M02Rik; AV066965; AW240712; CSL type zinc finger containing protein 3; CSL-type zinc finger-containing protein 3; DJC24_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4 homolog (JJJ3, S. cerevisiae); DPH4 homolog; DPH4, JJJ3 homolog; JJJ3; MmDjC7; RGD1564710; RP23-232D1.6; ZCSL3; Zinc finger, CSL domain containing 3; Zinc finger, CSL type containing 3. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 17kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DPH4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008] Function: Stimulates the ATPase activity of several Hsp70-type chaperones. Subunit: Monomer and homooligomer. Iron binding promotes oligomerization. Subcellular Location: Cytoplasm, cytoskeleton (By similarity). Similarity: Belongs to the DPH4 family. Contains 1 DPH-type zinc finger. Contains 1 J domain. Database links: Entrez Gene: 120526 Human Entrez Gene: 99349 Mouse Omim: 611072 Human SwissProt: Q6P3W2 Human SwissProt: Q91ZF0 Mouse Unigene: 187269 Human Unigene: 741895 Human Unigene: 25661 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |