產(chǎn)品編號 | bs-14409R-Gold |
英文名稱1 | Rabbit Anti-DOPEY1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的遲鈍蛋白家族1抗體 |
別 名 | Dopey-1; DOP1; DOP1_HUMAN; Dopey family member 1; DOPEY1; KIAA1117; Protein dopey 1; Protein dopey-1. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 277kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DOPEY1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Dopey-1 is a 2,465 amino acid protein that is thought to be involved in protein trafficking between the late golgi and early endosomes and may be involved in neurological alternations and mental retardation associated with Down syndrome. The gene encoding Dopey-1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function: May be involved in protein traffic between late Golgi and early endosomes. Similarity: Belongs to the dopey family. Database links: Entrez Gene: 23033 Human Entrez Gene: 320615 Mouse SwissProt: Q5JWR5 Human SwissProt: Q8BL99 Mouse Unigene: 520246 Human Unigene: 708998 Human Unigene: 245500 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |