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Rabbit Anti-FBG4/AP Conjugated antibody (bs-16031R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16031R-AP
英文名稱1 Rabbit Anti-FBG4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的FBG4蛋白抗體
別    名 F box only protein 17; F box only protein 26; F-box only protein 17; F-box only protein 26; F-box protein 17; F-box protein FBG4; FBX17; FBX17_HUMAN; FBX26; Fbxo17; FBXO26; FLJ11798; FLJ25205; FLJ58300; MGC9379.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBG4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins.

Tissue Specificity:
Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.

Similarity:
Contains 1 F-box domain.
Contains 1 FBA (F-box associated) domain.

Database links:

Entrez Gene: 115290 Human

Entrez Gene: 50760 Mouse

Entrez Gene: 292757 Rat

GenBank: NM_024907 Human

GenBank: NM_148169 Human

GenBank: NM_015796 Mouse

Omim: 609094 Human

SwissProt: Q96EF6 Human

SwissProt: Q9QZM8 Mouse

SwissProt: Q6AY27 Rat

Unigene: 531770 Human

Unigene: 358659 Mouse

Unigene: 53606 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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