| 產(chǎn)品編號(hào) | bs-19325R-Gold |
| 英文名稱1 | Rabbit Anti-NPAS4/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的神經(jīng)細(xì)胞PAS結(jié)構(gòu)域蛋白4抗體 |
| 別 名 | bHLH PAS type transcription factor NXF; bHLHe79; bHLHe79; Class E basic helix-loop-helix protein 79; HLH-PAS transcription factor NXF; Le PAS; limbic enhanced PAS protein; neuronal PAS domain protein 4; Neuronal PAS domain-containing protein 4; Neuronal PAS4; NPAS4; NPAS4_HUMAN; NXF; PAS domain-containing protein 10; PASD10. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 87kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NPAS4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] Function: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT. Subcellular Location: Nucleus. Tissue Specificity: Brain. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains. Database links: Entrez Gene: 266743 Human Entrez Gene: 225872 Mouse Entrez Gene: 724016 Zebrafish Omim: 608554 Human SwissProt: Q8IUM7 Human SwissProt: Q8BGD7 Mouse SwissProt: Q1ECW2 Zebrafish Unigene: 256036 Human Unigene: 287867 Mouse Unigene: 86654 Rat Unigene: 81110 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
