產(chǎn)品編號(hào) | bs-19265R-PE-Cy7 |
英文名稱1 | Rabbit Anti-NKIRAS2/PE-Cy7 Conjugated antibody |
中文名稱 | PE-Cy7標(biāo)記的核轉(zhuǎn)錄因子κB抑制作用Ras樣2蛋白抗體 |
別 名 | DKFZP434N1526; I kappa B interacting Ras like protein 2; I-kappa-B-interacting Ras-like protein 2; Kappa B Ras protein 2; Kappa B-Ras protein 2; KappaB Ras2; KappaB-Ras2; KBRAS 2; KBRAS2; KBRS2_HUMAN; MGC74742; NF kappa B inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras like 2; NFKB inhibitor interacting Ras like protein 2; NKIRAS 2; NKIRAS2. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) G蛋白信號(hào) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NKIRAS2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Similarity: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. Database links: Entrez Gene: 28511 Human Entrez Gene: 71966 Mouse Omim: 604497 Human SwissProt: Q9NYR9 Human SwissProt: Q9CR56 Mouse Unigene: 632252 Human Unigene: 274734 Mouse Unigene: 90866 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |