產(chǎn)品編號(hào) | bs-14530R-PE-Cy7 |
英文名稱1 | Rabbit Anti-EI2BL/PE-Cy7 Conjugated antibody |
中文名稱 | PE-Cy7標(biāo)記的EI2BL蛋白抗體 |
別 名 | EI2BL; M1Pi; Mediator of RhoA-dependent invasion; Methylthioribose 1 phosphate isomerase 1; Methylthioribose 1 phosphate isomerase homolog; Methylthioribose-1-phosphate isomerase; MGC3207; MRDI; mri1; MTNA; MTNA_HUMAN; MTR-1-P isomerase; S methyl 5 thioribose 1 phosphate isomerase 1; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF 2B; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein; Ypr118w. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 39kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EI2BL |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
Function: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. Subcellular Location: Nucleus. Cytoplasm. Cell projection. Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells. Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. Database links: Entrez Gene: 84245 Human Entrez Gene: 67873 Mouse Omim: 615105 Human SwissProt: Q9BV20 Human SwissProt: Q9CQT1 Mouse Unigene: 439370 Human Unigene: 278085 Mouse Unigene: 16390 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |