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Rabbit Anti-Neurexophilin 3/BF488 Conjugated antibody (bs-19211R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19211R-BF488
英文名稱1 Rabbit Anti-Neurexophilin 3/BF488 Conjugated antibody
中文名稱 BF488標記的神經外營養(yǎng)蛋白3抗體
別    名 KIAA1159; Neurexophilin-3; NPH3; Nxph3; NXPH-3; NXPH3_HUMAN; UNQ687/PRO1327.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neurexophilin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I Alpha(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.

Function:
May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins.

Subcellular Location:
Secreted.

Tissue Specificity:
Highest level in brain.

Post-translational modifications:
May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells.

Similarity:
Belongs to the neurexophilin family.

Database links:

Entrez Gene: 11248 Human

Entrez Gene: 104079 Mouse

Entrez Gene: 59315 Rat

Omim: 604636 Human

SwissProt: O95157 Human

SwissProt: Q91VX5 Mouse

SwissProt: Q9Z2N5 Rat

Unigene: 55069 Human

Unigene: 22970 Mouse

Unigene: 19736 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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