產(chǎn)品編號(hào) | bs-19211R-AP |
英文名稱1 | Rabbit Anti-Neurexophilin 3/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的神經(jīng)外營(yíng)養(yǎng)蛋白3抗體 |
別 名 | KIAA1159; Neurexophilin-3; NPH3; Nxph3; NXPH-3; NXPH3_HUMAN; UNQ687/PRO1327. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Pig, Rabbit, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 28kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Neurexophilin 3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I Alpha(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality. Function: May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins. Subcellular Location: Secreted. Tissue Specificity: Highest level in brain. Post-translational modifications: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells. Similarity: Belongs to the neurexophilin family. Database links: Entrez Gene: 11248 Human Entrez Gene: 104079 Mouse Omim: 604636 Human SwissProt: O95157 Human SwissProt: Q91VX5 Mouse Unigene: 55069 Human Unigene: 22970 Mouse Unigene: 19736 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |