產(chǎn)品編號(hào) | bs-19194R-PE |
英文名稱1 | Rabbit Anti-NEK10/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的絲氨酸/蘇氨酸蛋白激酶Nek10抗體 |
別 名 | FLJ32685; Never in mitosis A related kinase 10; NIMA (never in mitosis gene a) related kinase 10; NimA related protein kinase 10; Serine/threonine protein kinase Nek10. NEK10_HUMAN |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 133kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NEK10 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Nek10 is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10. Predicted molecular weight: 55 kDa for Isoform 5 (and 133 kDa for Isoform 1). Function: NEK10 belongs to the protein kinase superfamily; Ser/Thr protein kinase family; NIMA subfamily. Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. Contains 1 ARM repeat. Contains 1 protein kinase domain. Database links: Entrez Gene: 152110 Human Entrez Gene: 238944 Mouse SwissProt: Q6ZWH5 Human SwissProt: Q3UGM2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |