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Rabbit Anti-GPRASP2/BF594 Conjugated antibody (bs-15393R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-15393R-BF594
英文名稱1 Rabbit Anti-GPRASP2/BF594 Conjugated antibody
中文名稱 BF594標記的G蛋白偶聯(lián)受體GPRSP2蛋白抗體
別    名 FLJ35662; FLJ37327; G-protein coupled receptor-associated sorting protein 2; GASP-2; GASP2; GPRASP2; GASP2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉(zhuǎn)導  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 94kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPRASP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
G protein-coupled receptors play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GASP-2 (G protein-coupled receptor associated sorting protein 2), also known as GPRASP2, is an 838 amino acid protein that regulates a number of G-protein coupled receptors, such as CT-R (calcitonin receptor) and mAChR M1 (muscarinic acetylcholine receptor M1), through interactions with their cytoplasmic tails. Expressed primarily in brain, GASP-2 is a member of the GPRASP family and forms a complex with Huntingtin, with which it is thought to influence receptor trafficking.

Function:
May play a role in regulation of a variety of G-protein coupled receptors.

Subunit:
Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Expressed in the brain.

Similarity:
Belongs to the GPRASP family.

Database links:

Entrez Gene: 114928 Human

Entrez Gene: 245607 Mouse

GenBank: NP_001004051 Human

SwissProt: Q96D09 Human

SwissProt: Q8BUY8 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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