| 產(chǎn)品編號(hào) | bs-15393R-BF350 |
| 英文名稱1 | Rabbit Anti-GPRASP2/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的G蛋白偶聯(lián)受體GPRSP2蛋白抗體 |
| 別 名 | FLJ35662; FLJ37327; G-protein coupled receptor-associated sorting protein 2; GASP-2; GASP2; GPRASP2; GASP2_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 94kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPRASP2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: G protein-coupled receptors play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GASP-2 (G protein-coupled receptor associated sorting protein 2), also known as GPRASP2, is an 838 amino acid protein that regulates a number of G-protein coupled receptors, such as CT-R (calcitonin receptor) and mAChR M1 (muscarinic acetylcholine receptor M1), through interactions with their cytoplasmic tails. Expressed primarily in brain, GASP-2 is a member of the GPRASP family and forms a complex with Huntingtin, with which it is thought to influence receptor trafficking. Function: May play a role in regulation of a variety of G-protein coupled receptors. Subunit: Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR. Subcellular Location: Cytoplasmic Tissue Specificity: Expressed in the brain. Similarity: Belongs to the GPRASP family. Database links: Entrez Gene: 114928 Human Entrez Gene: 245607 Mouse GenBank: NP_001004051 Human SwissProt: Q96D09 Human SwissProt: Q8BUY8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
