產(chǎn)品編號(hào) | bs-15376R-Gold |
英文名稱1 | Rabbit Anti-GPR114/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的G蛋白偶聯(lián)受體GPR114蛋白抗體 |
別 名 | G protein coupled receptor 114; G-protein coupled receptor PGR27; GP114; GP114_HUMAN; GPR114; PGR27; Probable G-protein coupled receptor 114; UNQ2524/PRO6017. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 57kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPR114 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR114 (G protein-coupled receptor 114), also known as G-protein coupled receptor PGR27, is a 528 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Containing one GPS domain and mapping to human chromosome 16, GPR114 functions as an orphan receptor. Chromosome 16 encodes over 900 genes, comprises nearly 3% of the human genome and is associated with both Rubinstein-Taybi syndrome and Crohn's disease. Function: Orphan receptor. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Database links: Entrez Gene: 221188 Human SwissProt: Q8IZF4 Human Unigene: 187884 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |