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Rabbit Anti-GPCR RTA/MRGPRF/PE-Cy5 Conjugated antibody (bs-15372R-PE-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-15372R-PE-Cy5
英文名稱1 Rabbit Anti-GPCR RTA/MRGPRF/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的G蛋白偶聯(lián)受體RTA蛋白抗體
別    名 GPR140; GPR168; MGC21621; mrgF; MRGPRF; RTA; MRGRF_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPCR RTA
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
MRGF is a 343 amino acid multi-pass membrane protein that functions as an orphan receptor. MRGF belongs to the G-protein coupled receptor 1 family and Mas subfamily, and is thought to have a role in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGF maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Database links:

Entrez Gene: 219928 Human

Entrez Gene: 211577 Mouse

Entrez Gene: 266762 Rat

SwissProt: Q96AM1 Human

SwissProt: Q8VCJ6 Mouse

SwissProt: P23749 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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