產(chǎn)品編號 | bs-15372R-Gold |
英文名稱1 | Rabbit Anti-GPCR RTA/MRGPRF/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的G蛋白偶聯(lián)受體RTA蛋白抗體 |
別 名 | GPR140; GPR168; MGC21621; mrgF; MRGPRF; RTA; MRGRF_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 38kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPCR RTA |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: MRGF is a 343 amino acid multi-pass membrane protein that functions as an orphan receptor. MRGF belongs to the G-protein coupled receptor 1 family and Mas subfamily, and is thought to have a role in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGF maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Database links: Entrez Gene: 219928 Human Entrez Gene: 211577 Mouse SwissProt: Q96AM1 Human SwissProt: Q8VCJ6 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |