| 產(chǎn)品編號(hào) | bs-13303R-Gold |
| 英文名稱(chēng)1 | Rabbit Anti-GBP4/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的G蛋白結(jié)合蛋白4抗體 |
| 別 名 | GBP 4; GBP-4; GBP4; GBP4_HUMAN; GTP binding protein 4; GTP-binding protein 4; Guanine nucleotide binding protein 4; Guanine nucleotide-binding protein 4; Guanylate binding protein 4; Guanylate-binding protein 4; Mpa2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 73kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GBP4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: GBP4 is a 640 amino acid protein that localizes to the cytoplasm and belongs to the guanylate binding protein (GBP) family. Like other GBP proteins, GBP4 contains a conserved N-terminal GTP-binding domain and functions to bind and hydrolyze GTP, GDP and GMP, possibly playing a role in erythroid differentiation. The gene encoding GBP4 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the GBP family. Database links: UniProtKB/Swiss-Prot: Q96PP9.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
