產(chǎn)品編號 | bs-13486R-Gold |
英文名稱1 | Rabbit Anti-Golgin 97/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的高爾基體蛋白97抗體 |
別 名 | Gap junction protein alpha 4 37kD; GOGA1_HUMAN; Golga 1; Golga1; Golgi autoantigen golgin subfamily a 1; Golgi autoantigen golgin subfamily A member 1; Golgi autoantigen golgin subfamily a1.; Golgin A1; Golgin subfamily A member 1; Golgin-97; Golgin97; MGC33154. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞類型標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 88kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Golgin 9 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The GRIP family member, golgin 97, is a trans-Golgi network peripheral membrane protein with an extensive coiled-coil structure (67% alpha-helical content) and a C-terminal GRIP domain. Golgin 97 localizes exclusively on the cytoplasmic face of the Golgi and can form homodimers. Binding of golgin 97 to the Golgi membrane is mediated by the G protein family member, Arl1. Golgin 97 acts as an essential player to the cell in the form of a tethering molecule associating with tubulovesicular carriers during the trafficking from the trans-Golgi network to the recycling endosome and/or early endosome. During poxvirus infection, golgin 97 accumulates at the site of viral replication and is incorporated into virions. It associates with the insoluble fraction of the virus core protein, playing a significant role in virus replication and maturation of the virus membrane and core protein. Golgin 97 takes on a rod-like shape and, although it seemingly lacks a transmembrane domain, it protrudes from the surface of the virion envelope. Function: Probably involved in maintaining Golgi structure. Subunit: Binds RAB6A. Subcellular Location: Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Similarity: Contains 1 GRIP domain. Database links: Entrez Gene: 2800 Human Entrez Gene: 76899 Mouse Omim: 602502 Human SwissProt: Q92805 Human SwissProt: Q9CW79 Mouse Unigene: 133469 Human Unigene: 59504 Human Unigene: 131098 Mouse Unigene: 206017 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |