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Rabbit Anti-EXOC2/Gold Conjugated antibody (bs-13118R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13118R-Gold
英文名稱1 Rabbit Anti-EXOC2/Gold Conjugated antibody
中文名稱 膠體金標記的胞吐囊復合體蛋白2抗體
別    名 exocyst complex component 2; exocyst complex component Sec5; FLJ11026; SEC5; SEC5 like 1; SEC5L1; Sec5p; EXOC2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EXOC2/SEC5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The mammalian exocyst complex (sec 6/8) is a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Sec 5 is one of eight exocyst complex subunits: Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. Exocyst complex regulation depends upon Sec5 binding Ral in a GTP-dependent manner. Human Sec5 maps to chromosome 6p25.3.

Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Subunit:
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with RALA and GNEFR/DELGEF. Interaction with GNEFR occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALB.

Subcellular Location:
Plasma membrane.

Tissue Specificity:
Widely expressed with highest levels in brain and placenta.

Similarity:
Belongs to the SEC5 family.
Contains 1 IPT/TIG domain.

Database links:

Entrez Gene: 55770 Human

Entrez Gene: 66482 Mouse

Entrez Gene: 171455 Rat

SwissProt: Q96KP1 Human

SwissProt: Q9D4H1 Mouse

SwissProt: O54921 Rat

Unigene: 484412 Human

Unigene: 293510 Mouse

Unigene: 2869 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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