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Rabbit Anti-DMWD/RBITC Conjugated antibody (bs-13042R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13042R-RBITC
英文名稱1 Rabbit Anti-DMWD/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的強(qiáng)直性肌營養(yǎng)不良相關(guān)蛋白9抗體
別    名 dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica WD repeat containing protein; Dystrophia myotonica WD repeat-containing protein; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59; Protein DMR-N9.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DMWD/DMRN9
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.

Function:
Could have a regulatory function in meiosis.

Subcellular Location:
Contains 5 WD repeats.

Tissue Specificity:
Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen.

Similarity:
Contains 5 WD repeats.

Database links:

Entrez Gene: 1762 Human

Omim: 609857 Human

SwissProt: Q09019 Human

Unigene: 515474 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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