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Rabbit Anti-Calneuron 1/HRP Conjugated antibody (bs-12164R-HRP)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12164R-HRP
英文名稱1 Rabbit Anti-Calneuron 1/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的鈣營養(yǎng)蛋白1/鈣結合蛋白8抗體
別    名 CaBP8; CABP8_HUMAN; Calcium binding protein 8; Calcium binding protein; Calcium binding protein CABP8; Calcium-binding protein 8; Caln1; Calneuron I; Calneuron-1; Calneuron1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

Function:
Negatively regulates Golgi-to-plasma membranetrafficking by interacting with PI4KB and inhibiting its activity(By similarity). May play a role in the physiology of neurons andis potentially important in memory and learning.

Subunit:
Interacts with PI4KB. This binding competes withFREQ/NCS1 binding in a calcium-dependent manner.

Subcellular Location:
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.

Tissue Specificity:
Brain specific.

Similarity:
Contains 2 EF-hand domains.

Database links:

Entrez Gene: 83698 Human

Entrez Gene: 140904 Mouse

Entrez Gene: 363909 Rat

Omim: 607176 Human

SwissProt: Q9BXU9 Human

SwissProt: Q9JJG7 Mouse

SwissProt: Q06BI3 Rat

Unigene: 592750 Human

Unigene: 320206 Mouse

Unigene: 202895 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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