產(chǎn)品編號(hào) | bs-13979R-Gold |
英文名稱1 | Rabbit Anti-COPG2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的外殼蛋白γ2-COP抗體 |
別 名 | 2 COP; Coat protein nonclathrin gamma 2 cop; Coatomer protein complex subunit gamma 2; Coatomer subunit gamma 2; Coatomer subunit gamma-2; COPG 2; Copg2; COPG2_HUMAN; DKFZp761N09121; FLJ11781; Gamma 2 coat protein; Gamma 2 COP; Gamma-2-coat protein; Gamma-2-COP. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 98kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COPG2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Subcellular Location: Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Similarity: Belongs to the COPG family. Contains 6 HEAT repeats. Database links: Entrez Gene: 26958 Human Entrez Gene: 54160 Mouse Omim: 604355 Human SwissProt: Q9UBF2 Human SwissProt: Q9QXK3 Mouse Unigene: 6421 Human Unigene: 381860 Mouse Unigene: 39896 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |