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Rabbit Anti-USE1/PE-Cy7 Conjugated antibody (bs-12305R-PE-Cy7)
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12305R-PE-Cy7
英文名稱1 Rabbit Anti-USE1/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的囊泡轉(zhuǎn)運蛋白Use1抗體
別    名 2010315L10Rik; 5730403H22Rik; AV002165; D12; Ed2; Embryonic development factor 2; MDS032; P31; Protein D12; Protein p31; putative MAPK activating protein PM26; Putative MAPK-activating protein PM26; Q-snare; RGD1306660; SLT1; SNARE-like tail-anchored protein 1 homolog; Unconventional SNARE in the ER 1 homolog (S. cerevisiae); Unconventional SNARE in the ER 1 homolog; Use1; USE1 like protein; Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae); USE1-like protein; USE1_HUMAN; USE1L; Vesicle transport protein USE1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human USE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.

Function:
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

Subunit:
Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the USE1 family.

Database links:

Entrez Gene: 512890 Cow

Entrez Gene: 55850 Human

Entrez Gene: 67023 Mouse

Entrez Gene: 290627 Rat

Omim: 610675 Human

SwissProt: Q9NZ43 Human

SwissProt: Q9CQ56 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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