| 產(chǎn)品編號(hào) | bs-12129R-BF488 |
| 英文名稱(chēng)1 | Rabbit Anti-ACCN4/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標(biāo)記的腦鈉通道蛋白4抗體 |
| 別 名 | Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 70kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ACCN4/ASIC4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]. Function: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Subunit: Homotrimer or heterotrimer with other ASIC proteins. Subcellular Location: .Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. Similarity: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily. Database links: Entrez Gene: 55515 Human Entrez Gene: 241118 Mouse Omim: 606715 Human SwissProt: Q96FT7 Human SwissProt: Q7TNS7 Mouse Unigene: 87469 Human Unigene: 110790 Mouse Unigene: 44831 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
